NICOTINAMIDE INCREASES INTRACELLULAR NAD+ CONTENT TO ENHANCE AUTOPHAGY-MEDIATED GROUP A STREPTOCOCCAL CLEARANCE IN ENDOTHELIAL CELLS

Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells

Group A streptococcus (GAS) is a versatile pathogen that causes a wide spectrum of diseases in humans.Invading host cells is a known strategy for GAS to avoid antibiotic killing and immune recognition.However, the underlying ACTIVE mechanisms of GAS resistance to intracellular killing need to be explored.Endothelial HMEC-1 cells were infected with

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Effects of extract solution from magnesium alloys supplemented with different compositions of rare earth elements on in vitro epithelial and osteoblast progenitor cells

Background: Magnesium alloys (Mg-alloys) have gained significant attention in recent years as a potential bioactive material for clinical applications.The incorporation of rare earth elements (REEs) into Mg-alloys has been of particular interest due to their potential to improve both mechanical and biological properties.Although there are diverse O

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Hem-o-lok clip found in the common bile duct 3 years after laparoscopic cholecystectomy and surgical exploration

Endoscopic retrograde cholangiopancreatography (ERCP) with stone extraction is a common and preferred choice for gallstone disease.Laparoscopic common bile duct exploration (LCBDE) and laparoscopic cholecystectomy (LC) are being increasingly used for managing choledocholithiasis and cholecystolithiasis.We report a case of a Hem-o-lok clip that was

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